VRTX

Vertex Pharmaceuticals Incorporated ·Nasdaq Global Select·Healthcare
525.77 live · 2026-08-12 15:59
85.7%
Brown Bear Score
85.5%
Business Conviction Score
77.0%
Position Health Score
54.6%
Chase Risk
Daily closes

Daily closes · 1Y (252 sessions) · +35.6% · range 376.62–529.65

The Businesswhat the company reports

Business & cash flow

FCF / assets 12.5%
OCF / assets 14.2%
FCF / revenue 30.3%
Gross margin 55.0%
ROIC 21.4%
Forward P/E 24.1

FCF/assets and OCF/assets are the cash-flow measures Brown Bear's own testing found to survive; FCF/revenue is shown alongside for context. Assets are from the latest annual filing (FY2025).

Price vs Earnings growth

Price has run ahead of forward EPS growth by 7.6pp

Confidence 95.0/100

Takeaway Price and forward earnings growth are broadly in step; no strong valuation lean either way.

Reported earnings

Next report 2026-11-02 · consensus EPS 4.89

Q2 23 revenue: 2.49bnQ2 23 net income: 915.70mQ2 23 EPS: 3.52Q3 23 revenue: 2.48bnQ3 23 net income: 1.04bnQ3 23 EPS: 3.97Q3 23Q4 23 revenue: 2.52bnQ4 23 net income: 968.80mQ4 23 EPS: 3.72Q1 24 revenue: 2.69bnQ1 24 net income: 1.10bnQ1 24 EPS: 4.21Q1 24Q2 24 revenue: 2.65bnQ2 24 net income: -3.59bnQ2 24 EPS: -13.92Q3 24 revenue: 2.77bnQ3 24 net income: 1.05bnQ3 24 EPS: 4.01Q3 24Q4 24 revenue: 2.91bnQ4 24 net income: 913.00mQ4 24 EPS: 3.54Q1 25 revenue: 2.77bnQ1 25 net income: 646.30mQ1 25 EPS: 2.49Q1 25Q2 25 revenue: 2.96bnQ2 25 net income: 1.03bnQ2 25 EPS: 3.99Q3 25 revenue: 3.08bnQ3 25 net income: 1.08bnQ3 25 EPS: 4.20Q3 25Q4 25 revenue: 3.19bnQ4 25 net income: 1.19bnQ4 25 EPS: 4.62Q1 26 revenue: 2.99bnQ1 26 net income: 1.03bnQ1 26 EPS: 4.02Q1 26

Revenue Net incomeEPS (GAAP) (-13.92–4.62, own scale) Derived Q4

12 quarters to Q1 26. Revenue and net income share one scale, so the gap between them is the margin. The baseline is zero — bars below it are losses. The line is GAAP EPS — it spans every quarter shown, where the reported figure only goes back as far as the consensus feed does.

Quarter endingRevenueYoY Net incomeEPS (GAAP) EPS reportedvs consensus Filed
2026-03-31 2.99bn +7.8% 1.03bn 4.02 4.47 +1.7% 2026-05-05
2025-12-31 (derived) 3.19bn +9.5% 1.19bn 4.62 5.03 -2.8% 2026-02-13
2025-09-30 3.08bn +11.0% 1.08bn 4.20 4.80 +3.1% 2025-11-04
2025-06-30 2.96bn +12.1% 1.03bn 3.99 2025-08-05

Earnings response

Typical move around a filing ±4.2%
On an ordinary two days ±1.3% — filings move it 3.2× as much
Direction 5 up, 7 down over 12 filings
Revenue change and price reaction, by quarter
Q2 22 revenue +22.5% year on yearQ2 22 filed 2022-08-05: price +6.9%Q3 22 revenue +17.6% year on yearQ3 22 filed 2022-10-28: price +8.4%Q3 22Q1 23 revenue +13.2% year on yearQ1 23 filed 2023-05-02: price +0.4%Q2 23 revenue +13.5% year on yearQ2 23 filed 2023-08-02: price +0.0%Q2 23Q3 23 revenue +6.4% year on yearQ3 23 filed 2023-11-07: price -2.3%Q1 24 revenue +13.3% year on yearQ1 24 filed 2024-05-07: price +4.1%Q1 24Q2 24 revenue +6.1% year on yearQ2 24 filed 2024-08-02: price -5.7%Q3 24 revenue +11.6% year on yearQ3 24 filed 2024-11-05: price +4.4%Q3 24Q1 25 revenue +3.0% year on yearQ1 25 filed 2025-05-06: price -13.1%Q2 25 revenue +12.1% year on yearQ2 25 filed 2025-08-05: price -18.3%Q2 25Q3 25 revenue +11.0% year on yearQ3 25 filed 2025-11-04: price -2.1%Q1 26 revenue +7.8% year on yearQ1 26 filed 2026-05-05: price -0.5%Q1 26

Revenue up year on year Revenue down Price move around the filing separate scales — a crossing means nothing

Quarter endingFiledRevenue YoY Move around filingNext 20 sessions vs SPY
2026-03-31 2026-05-05 +7.8% -0.5% +0.1%
2025-09-30 2025-11-04 +11.0% -2.1% +8.7%
2025-06-30 2025-08-05 +12.1% -18.3% +0.3%
2025-03-31 2025-05-06 +3.0% -13.1% -3.6%

Share count

Diluted shares over time

Diluted shares Return since the previous filing

Direction Shrinking — shares retired
Diluted shares 256.3M as at 2026-03-31
Change over 1 year -1.2%
Change over 3 years -1.5%
Public float $113.40bn as at 2025-06-30 (10-K)

The Pricewhat the chart is doingTop ↑

Price Levels

StrategyFair Value Anchor
Reference band 484.99 — 528.36
Protective stop 472.73 (Atr, 6.7% risk)
Support 465.78 (4 touches, 12.9% away)
Resistance (— away)

Takeaway The shares are about 12.9% above 465.78, a price buyers have stepped in at before. There is no ceiling to point to, because the stock is trading where it has not traded before and nobody has sold it at these levels. That floor has held 4 times, which is how it was spotted. If someone bought at today's price and sold if it dropped through the level below, they would be about 6.7% out of pocket. That is all this figure means — an illustration of the risk, not a price to sell at.

Levels are computed from price structure. They describe where the engine locates support and extension — they are not targets, and not advice.

Ichimoku Cloud (Adaptive)

Daily cloudPrice ABOVE the cloud | periods 6/17/33 (64% of classic 9/26/52)
LinesTenkan/Kijun BULL (fresh up cross, 2d ago) | cloud twist BULL (fresh up, 0d ago)
Cloud eventFresh up breakout 2d ago
Cloud thickness8% percentile (thin — little structure to fight through)
Chikou spanAbove price from 26 periods ago
Weekly cloudPrice ABOVE the weekly cloud (context only, not scored)

Takeaway The stock is trading above its cloud — a shaded band drawn from several of its own moving averages, currently 505.58 to 506.86. Being above it means the medium-term picture is pointing upwards, and that band is the first place the stock has recent support if it slips back. Its shorter-term averages agree with that.

Trailing returns

21 days +10.4%
63 days +17.3%
126 days +13.4%
252 days +40.4%
Below 252d high0.7%

Trend context

PositionFar above trend
ExtensionExtremely extended
Trend slopeFlat
Direction of travelDiverging from trend

Takeaway Extreme upside extension is still moving away from fair trend; chase risk is elevated.

Volatility

State Expanded out of a squeeze
Current band width14.4% of price
Recent tightest4.2% (4 sessions ago, narrower than 99.0% of its history)
Expansion since3.40×
Range broken Up
Band 452.98 — 523.26

Takeaway Lately this share price has been swinging around inside a range roughly 14% wide, and it recently went unusually quiet — calmer than it has been 99% of the time. It has started moving again since, swinging about 3.4 times as widely as during that quiet spell, and it broke upwards. A stock that has been quiet tends to make its next move look big by comparison, simply because the recent bar was low.

Historical trends

0255075100Share price 470.72–529.652026-07-032026-08-12
Position Health Business Conviction Share price

History begins when the site started recording, not when the company listed, so a short line means a short record and nothing more.

Who's Tradingthe flow behind the priceTop ↑

Insider activity

ActivityInsider selling
Buy filings0
Sell filings6
Shares sold9,547
Value sold$4.6m
Latest sell2026-07-02
FiledInsiderSharesValue
2026-07-02 Sold Tatsis OuraniaEVP, Chief Reg. & Quality Off. 1,500 $787,485
2026-07-02 Sold McKechnie DuncanEVP, Chief Commercial Officer 1,541 $799,779

Open-market Form 4 purchases and sales over the last 75 days, read from SEC EDGAR Form 4. Grants, option exercises, gifts and shares withheld for tax are excluded — they are compensation mechanics, not a decision to buy or sell. Reported Form 4 activity. Brown Bear tested insider cluster-buying as a return signal and rejected it as era-unstable; shown as fact, not signal.

Volume confirmation

Volume-price trend Above its signal line
Confirmation Marginal

No absorption or distribution event in the recent window.

Takeaway Slightly more shares change hands on rising days than on falling ones, but the gap is too small to read anything into.

Options Positioning

No binary-event flag

VRTX: no binary-event flag. Near IV 25%, far IV 26% (ratio 0.95), implied move 3.1%.

Implied volatility 25% near (9d) · 26% far (65d)
Term structure 0.95× near/far
Historical volatility 28%
Implied vs historical 0.89×
Implied move ±3.1% by 2026-08-21
Implied move vs ATR 0.40×
Skew Put Skew (3.81×)
Call wall 550.00 (+4.6% away)
Put wall 480.00 (-8.7% away)
Gamma pin 480.00

Takeaway Insuring against a move in this stock costs less for the next few weeks than for the next few months, which is the normal state of affairs and suggests no particular date is worrying anyone. Options traders are positioned for a move of around 3.1% in either direction by 2026-08-21.

Chain as at 2026-08-12. This is a risk read on whether a specific event is being priced — not a directional view.

Context & Methodthe record, and how it was builtTop ↑

Relative Rotation

ImprovingLeadingLaggingWeakeningvs sectorvs SPYsector vs SPYRS-Ratio →RS-Momentum →

Stock Leadership Confirmed

Rotation health 82.3/100; Strong Rotation Tailwind.

Rotation health 82.3
Rotation strength 69.8
LegQuadrantRS-RatioRS-Mom
Stock vs sector Leading 108.0 120.5
Stock vs SPY Leading 100.4 121.2
Sector vs SPY Improving 86.4 102.1

Direction of travel: North-East / strengthening leadership

Position only. Brown Bear's RRG redesign programme is closed — five constructions, none beat an appropriate null — so this section describes where the name sits, and is not a signal.

News Headlines

  1. Loading headlines\u2026

Headlines are supplied by third-party feeds and are not written, ranked or interpreted by Brown Bear. They feed no score on this page.

Detailed Scoring

Positive signals

  • Piotroski F-score 6/9 (+15.0)
  • Altman Z-score 20.93 (+10.0)
  • Insider conviction score (+3.0)
  • Gross margin quality: 55.0% (+12.8)
  • ROIC quality: 21.4% (+14.0)
  • FCF margin quality: 30.3% (+20.0)
  • ROIC improving by 19.9 pts (+10.0)
  • FCF margin improving by 34.7 pts (+5.0)
  • High earnings quality (accrual ratio 0.013) (+2.0)
  • Track 1: MACD histogram state (4.93) (+8.0)
  • Track 1: relative strength trend improving (+5.0)
  • Track 1: 20-day momentum acceleration 0.04 (+3.0)
  • Track 1: bullish DI spread 30.1 (+8.0)
  • Track 1: ADX 25.3 and rising (+5.0)
  • Track 1: relative momentum rank 0.77 (+3.6)
  • Track 1: Bullish MACD divergence (+12.0)
  • Track 1: EMA20 reclaim distance 6.4% (+2.8)
  • Track 1: EMA20 slope improving 2.7% (+5.0)
  • Track 1: MACD histogram acceleration 6.18 (+10.0)
  • Track 1: positive MACD regime (+3.0)
  • Track 1: MACD line/signal repair quality (+10.0)
  • Track 1: MACD slope improving (+5.0)
  • Track 1: VPT strength 0.09 (+1.8)
  • Track 1: price above EMA50 by 9.4% (+5.0)
  • Track 1: EMA50 slope improving 1.8% (+3.0)
  • Regime convergence: ICHIMOKU_CLOUD_REVERSAL confidence 100.0/100 (EXCEPTIONAL) (+20.0)

Negative signals

  • Track 1: RSI deterioration/extension 76.0, 5-day change +26.8
  • Chase risk 54.6/100 (Elevated Chase Risk): RSI 76.0, EMA20 6.4%, EMA50 9.4%, BB 1.04, distribution 4.5/100
  • Gross margin improving by -31.1 pts (+-3.0)
  • Chase risk 54.6/100 | Extension score 45.4/100 | Elevated Chase Risk